INT312662

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 0.10
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (DSE) nucleoplasm (CSTF2) Golgi apparatus (DSE)
endoplasmic reticulum (DSE) RNA binding (CSTF2) nucleolus (CSTF2)
Anatomy Link Frequency
Shell 2
poly 1
CSTF2 (Homo sapiens)
DSE (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 5 95.12 Very High Very High Very High
adenocard 15 79.88 Quite High
melanocortin 1 receptor 20 64.00 Quite High
cerebral cortex 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cytomegalovirus Infection 15 52.08 Quite High
Contagious Ecthyma 30 49.12 Quite Low
Obesity 5 42.56 Quite Low
Disease 5 5.00 Very Low Very Low Very Low
Breast Cancer 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, the fact that a strong CstF–DSE interaction allows 3?
CstF Binding (interaction) of DSE
1) Confidence 0.06 Published 2010 Journal EMBO J Section Body Doc Link PMC2876958 Disease Relevance 0.05 Pain Relevance 0.22
This supports the growing understanding that the CstF–DSE interaction represents a critical regulatory step for poly(A) site choice (Takagaki et al, 1996; Takagaki and Manley, 1998; Veraldi et al, 2001; Phillips et al, 2004; Shell et al, 2005).
CstF Binding (interaction) of DSE in Shell
2) Confidence 0.06 Published 2010 Journal EMBO J Section Body Doc Link PMC2876958 Disease Relevance 0 Pain Relevance 0.04
Finally, the fact that a strong CstF–DSE interaction allows 3?
CstF Binding (interaction) of DSE
3) Confidence 0.06 Published 2010 Journal EMBO J Section Body Doc Link PMC2876958 Disease Relevance 0.05 Pain Relevance 0.22
This supports the growing understanding that the CstF–DSE interaction represents a critical regulatory step for poly(A) site choice (Takagaki et al, 1996; Takagaki and Manley, 1998; Veraldi et al, 2001; Phillips et al, 2004; Shell et al, 2005).
CstF Binding (interaction) of DSE in Shell
4) Confidence 0.06 Published 2010 Journal EMBO J Section Body Doc Link PMC2876958 Disease Relevance 0 Pain Relevance 0.04
Thus, we propose that many noncanonical poly(A) sites may, similar to MC4R, predominantly rely on a potent DSE mediating a tight interaction with CstF.
CstF Binding (interaction) of DSE in poly
5) Confidence 0.06 Published 2010 Journal EMBO J Section Body Doc Link PMC2876958 Disease Relevance 0 Pain Relevance 0

General Comments

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