INT312751

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Gria1, GRIA1) plasma membrane (Gria1, GRIA1) cytosol (Gria1)
signal transduction (GRIA1) protein complex (Gria1)
Anatomy Link Frequency
hippocampus 2
Gria1 (Rattus norvegicus)
GRIA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
long-term potentiation 42 98.24 Very High Very High Very High
Hippocampus 12 97.40 Very High Very High Very High
amygdala 31 74.88 Quite High
antagonist 15 69.88 Quite High
agonist 9 69.28 Quite High
GABAergic 12 68.92 Quite High
Locus ceruleus 8 5.00 Very Low Very Low Very Low
depression 8 5.00 Very Low Very Low Very Low
Dopamine 4 5.00 Very Low Very Low Very Low
Pyramidal cell 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 27 86.24 High High
Depression 8 5.00 Very Low Very Low Very Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Aids-related Complex 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Amnesia 1 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A recent study has shown that norepinephrine-driven phosphorylation of GluR1 subunit may facilitate AMPA receptor trafficking to synaptic sites and LTP induction in the hippocampus [75].
Phosphorylation (phosphorylation) of GluR1 in hippocampus Spec (may) Positive_regulation (facilitate) of AMPA associated with hippocampus and long-term potentiation
1) Confidence 0.18 Published 2010 Journal Mol Brain Section Body Doc Link PMC2877027 Disease Relevance 0.22 Pain Relevance 0.55

General Comments

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