INT312770

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.12
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (CETP) transport (CETP) extracellular space (CETP)
small molecule metabolic process (CETP) extracellular region (CETP) lipid metabolic process (CETP)
CETP (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 15 74.32 Quite High
Bile 11 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 130 99.96 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

35 94.88 High High
Diabetes Mellitus 120 94.36 High High
Increased Venous Pressure Under Development 6 85.76 High High
Pressure And Volume Under Development 8 79.68 Quite High
INFLAMMATION 16 74.32 Quite High
Liver Disease 14 69.48 Quite High
Hyperlipidemia 7 54.60 Quite High
Cardiovascular Disease 38 53.72 Quite High
Cirrhosis 17 47.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An increase in PLTP would lead to larger HDL particles, while an enhancement in CETP and a decrease in LCAT would result in smaller HDL particles with an increase in the HDL3 sub-fraction.
Positive_regulation (enhancement) of Negative_regulation (decrease) of CETP associated with disorder of lipid metabolism
1) Confidence 0.12 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2877049 Disease Relevance 1.06 Pain Relevance 0.04
This finding has lead to the speculation that CETP inhibition may increase HDL-C levels, and several CETP inhibitors are in development.
Positive_regulation (increase) of Negative_regulation (inhibition) of CETP associated with disorder of lipid metabolism
2) Confidence 0.09 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC3022752 Disease Relevance 0.97 Pain Relevance 0

General Comments

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