INT312771

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.76
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (CETP) transport (CETP) extracellular space (CETP)
small molecule metabolic process (CETP) extracellular region (CETP) lipid metabolic process (CETP)
Anatomy Link Frequency
liver 2
CETP (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 30 35.76 Quite Low
fibrosis 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Liver Disease 28 100.00 Very High Very High Very High
Disorder Of Lipid Metabolism 148 97.16 Very High Very High Very High
Cirrhosis 34 93.80 High High
Targeted Disruption 6 58.60 Quite High
INFLAMMATION 32 35.76 Quite Low
Disease 8 18.76 Low Low
Stress 20 5.00 Very Low Very Low Very Low
Fibrosis 6 5.00 Very Low Very Low Very Low
Hepatotoxicity 4 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although reduced LCAT activity is common in a variety of liver diseases [46], the current report is, to the best of our knowledge, the first to identify increased CETP and PLTP activities as being associated with chronic liver impairment.
Negative_regulation (reduced) of Positive_regulation (increased) of CETP in liver associated with liver disease
1) Confidence 0.13 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2877049 Disease Relevance 0.84 Pain Relevance 0
The combination of decreased LCAT and increased CETP activities in the patients probably resulted in the increase in small HDL particles.
Negative_regulation (decreased) of Positive_regulation (increased) of CETP associated with disorder of lipid metabolism
2) Confidence 0.11 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2877049 Disease Relevance 0.92 Pain Relevance 0

General Comments

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