INT312829

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Context Info
Confidence 0.50
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.73
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ins2) extracellular region (Ins2) nucleus (Ins2)
carbohydrate metabolic process (Ins2) cytoplasm (Ins2)
Ins2 (Mus musculus)
Pain Link Frequency Relevance Heat
diabetic neuropathy 106 76.24 Quite High
Sciatic nerve 42 18.36 Low Low
sodium channel 10 5.00 Very Low Very Low Very Low
Neuropathic pain 6 5.00 Very Low Very Low Very Low
Action potential 6 5.00 Very Low Very Low Very Low
Nav1.6 2 5.00 Very Low Very Low Very Low
hyperexcitability 2 5.00 Very Low Very Low Very Low
analgesia 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
nav1.3 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 2 98.24 Very High Very High Very High
Diabetes Mellitus 78 86.40 High High
Hyperglycemia 40 84.32 Quite High
Peripheral Neuropathy 106 76.24 Quite High
Diabetic Neuropathy 2 50.00 Quite Low
Neuropathic Pain 14 5.00 Very Low Very Low Very Low
Congenital Anomalies 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A recent report suggested that the intracellular accumulation of the misfolded Proinsulin 2 leads to progressive disruption of the insulin secretory pathway organelle architecture and thereby resulting in pancreatic ?
Positive_regulation (leads) of Positive_regulation (accumulation) of Proinsulin
1) Confidence 0.50 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2877074 Disease Relevance 0.85 Pain Relevance 0.20
A recent report suggested that the intracellular accumulation of the misfolded Proinsulin 2 leads to progressive disruption of the insulin secretory pathway organelle architecture and thereby resulting in pancreatic ?
Positive_regulation (resulting) of Positive_regulation (accumulation) of Proinsulin
2) Confidence 0.50 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2877074 Disease Relevance 0.89 Pain Relevance 0.21

General Comments

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