INT312888
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Further, a genome-wide phosphoprotein survey has shown that this site on HDAC6 is phosphorylated [18]. | |||||||||||||||
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may directly phosphorylate HDAC6 at this site, although further work with purified proteins is needed to determine whether this is the case. | |||||||||||||||
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The function of HDAC6 phosphorylation | |||||||||||||||
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Using a phosphoepitope-specific antibody, we showed that phosphorylation of HDAC6 at serine-22, which conforms to the consensus site for GSK3? | |||||||||||||||
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Using a commercially available antibody (Abcam, ab61058, HDAC6-phospho S22), we found that inhibiting GSK3? | |||||||||||||||
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Various phosphorylation site prediction methods have indicated that serine-22 in murine and rat HDAC6 (corresponding to serine-21 in human HDAC6) may be phosphorylated by GSK3?. | |||||||||||||||
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Using a phosphoepitope-specific antibody, we showed that phosphorylation of HDAC6 at serine-22, which conforms to the consensus site for GSK3? | |||||||||||||||
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It has been shown that HDAC6 is a phosphoprotein [18], [19], but neither the kinases that are responsible for phosphorylating HDAC6 nor the effect of phosphorylation on this deacetylase have been established. | |||||||||||||||
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It has been shown that HDAC6 is a phosphoprotein [18], [19], but neither the kinases that are responsible for phosphorylating HDAC6 nor the effect of phosphorylation on this deacetylase have been established. | |||||||||||||||
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