INT312894

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.30
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (Gsk3b, Hdac6) cytoplasm (Gsk3b, Hdac6) cytosol (Gsk3b, Hdac6)
nucleus (Gsk3b, Hdac6) cell differentiation (Gsk3b) intracellular (Hdac6)
Gsk3b (Mus musculus)
Hdac6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 2 77.68 Quite High
cerebral cortex 2 77.04 Quite High
imagery 10 60.72 Quite High
depression 2 48.84 Quite Low
fluoxetine 6 43.88 Quite Low
sSRI 4 43.40 Quite Low
agonist 4 5.00 Very Low Very Low Very Low
Serotonin 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 28 99.96 Very High Very High Very High
Infection 4 74.32 Quite High
Stress 2 63.24 Quite High
Depression 2 48.84 Quite Low
Targeted Disruption 2 22.72 Low Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, it is possible that, in Alzheimer's disease, aberrant HDAC6 levels are induced by increased activity of GSK3?
GSK3 Binding (activity) of Positive_regulation (induced) of Gene_expression (levels) of HDAC6 associated with disease
1) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2877100 Disease Relevance 0.65 Pain Relevance 0.13
Moreover, it is possible that, in Alzheimer's disease, aberrant HDAC6 levels are induced by increased activity of GSK3?
GSK3 Binding (activity) of Positive_regulation (induced) of Gene_expression (aberrant) of HDAC6 associated with disease
2) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2877100 Disease Relevance 0.65 Pain Relevance 0.13

General Comments

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