INT312927

Context Info Confidence 0.29 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.07 Pain Relevance 0.08

nucleus (Hes3) DNA binding (Hes3) transcription factor binding (Hes3)

Hes3 (Mus musculus)

Pain Link Frequency Relevance Heat withdrawal 5 95.40 Perioperative pain 2 5.00 imagery 2 5.00 cytokine 1 5.00 Central nervous system 1 5.00 anesthesia 1 5.00 isoflurane 1 5.00 Hippocampus 1 5.00

Disease Link Frequency Relevance Heat Vibrio Infection 23 70.40 Neurological Disease 3 5.00 Cancer 3 5.00 Disease 3 5.00 Stroke 3 5.00 Camurati-engelmann Disease 2 5.00 Post Operative Pain 2 5.00 Stress 2 5.00 Glioblastoma 1 5.00 Bordatella Infection 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

(Eventually, after approximately a total of 7 days of differentiation, all Hes3 signal is lost [25]).

Negative_regulation (lost) of Hes3

1) Confidence 0.29 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2877108 Disease Relevance 0.07 Pain Relevance 0.08

General Comments

This test has worked.