INT312943

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.67 Pain Relevance 0.03

nucleus (Hes3) plasma membrane (ANTXR1) DNA binding (Hes3) transcription factor binding (Hes3)

ANTXR1 (Homo sapiens) Hes3 (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 1 55.24 Central nervous system 1 44.60 withdrawal 5 5.00 Perioperative pain 2 5.00 imagery 2 5.00 anesthesia 1 5.00 isoflurane 1 5.00 Hippocampus 1 5.00

Disease Link Frequency Relevance Heat Vibrio Infection 23 100.00 Stress 2 87.88 Disease 3 23.16 Stroke 3 22.20 Injury 1 6.04 Neurological Disease 3 5.00 Cancer 3 5.00 Camurati-engelmann Disease 2 5.00 Post Operative Pain 2 5.00 Glioblastoma 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Our findings show that cholera toxin regulates the expression and localization of Tie2 and Hes3 and induces powerful expansion of cultured NSCs.

cholera toxin Regulation (regulates) of Gene_expression (expression) of Hes3 associated with vibrio infection

1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2877108 Disease Relevance 0.67 Pain Relevance 0.03

General Comments

This test has worked.