INT313007

Context Info Confidence 0.07 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.30 Pain Relevance 0

Anatomy Link Frequency plasma 1 bc (Mus musculus)

Pain Link Frequency Relevance Heat Inflammatory response 36 50.00 Inflammation 40 20.72 alcohol 4 5.56 cytokine 8 5.00 ketamine 2 5.00 anesthesia 2 5.00 isoflurane 2 5.00

Disease Link Frequency Relevance Heat Stress 2 70.68 Targeted Disruption 14 62.08 Lung Cancer 14 59.44 Nicotine Addiction 30 54.12 INFLAMMATION 76 50.00 Communicable Diseases 2 27.04 Infection 14 24.56 Congenital Anomalies 2 22.80 Night Blindness 2 21.92 Cancer 6 12.84

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

There were some interesting, unexpected changes in BC metabolite levels upon BC supplementation in Bcmo1?

Negative_regulation (supplementation) of BC

1) Confidence 0.07 Published 2010 Journal Cell Mol Life Sci Section Body Doc Link PMC2877315 Disease Relevance 0 Pain Relevance 0

The 267A>T and 379C>T polymorphisms in the BCMO1 gene are common with variant allele frequencies of 42 and 24%, respectively, in Caucasian population of the United Kingdom, and result in increased BC and decreased BC metabolite concentrations in plasma [18, 19].

Negative_regulation (decreased) of BC in plasma

2) Confidence 0.07 Published 2010 Journal Cell Mol Life Sci Section Body Doc Link PMC2877315 Disease Relevance 0.30 Pain Relevance 0

General Comments

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