INT3131

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Context Info
Confidence 0.34
First Reported 1978
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.68
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Arc) plasma membrane (Arc) cytoskeleton organization (Arc)
cytoplasm (Arc)
Anatomy Link Frequency
dendrites 1
Arc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 35 99.68 Very High Very High Very High
cocaine 105 99.32 Very High Very High Very High
Central nervous system 37 91.48 High High
tolerance 18 91.12 High High
antagonist 4 84.72 Quite High
anesthesia 7 81.72 Quite High
nMDA receptor 1 80.24 Quite High
Somatostatin 1 52.80 Quite High
Inflammation 1 10.08 Low Low
long-term potentiation 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aids-related Complex 148 100.00 Very High Very High Very High
Convulsion 1 95.64 Very High Very High Very High
Targeted Disruption 4 95.56 Very High Very High Very High
Retinal Degeneration 29 91.12 High High
Impaired Glucose Tolerance 18 91.12 High High
Cognitive Disorder 14 71.20 Quite High
Hyperinsulinism 3 56.32 Quite High
Hyperglycemia 3 55.64 Quite High
Apoptosis 3 51.28 Quite High
Hypoglycemia 1 27.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast to Arc and Zif268, no
Arc Binding (contrast) of associated with aids-related complex
1) Confidence 0.34 Published 2008 Journal Neural Plasticity Section Body Doc Link PMC2631155 Disease Relevance 0.55 Pain Relevance 0
It was shown that Arc mRNA is constitutively expressed within the cell body, but is delivered into dendrites and accumulated at synapses upon an appropriate stimulus, such as a single electroconvulsive seizure (Lyford et al 1995).
Arc mRNA Binding (delivered) of in dendrites associated with convulsion and aids-related complex
2) Confidence 0.25 Published 2008 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2699806 Disease Relevance 0.85 Pain Relevance 0.07
Further, with an insulin infusion that produces postprandial levels, we found that ARC GLP-1, compared with saline, inhibited glucose production by ?
ARC Binding (compared) of associated with aids-related complex
3) Confidence 0.22 Published 2008 Journal Diabetes Section Body Doc Link PMC2494674 Disease Relevance 0.65 Pain Relevance 0.28
Interestingly, Dnm2 is regulated by the transcription factor Arc, also altered in the NAc with cocaine [12,65].
Arc Binding (altered) of associated with nucleus accumbens, aids-related complex and cocaine
4) Confidence 0.15 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2837051 Disease Relevance 0.26 Pain Relevance 0.37
EM. regions were ineffective when applied to the ARC-VMH region.
ARC-VMH Binding (applied) of associated with aids-related complex
5) Confidence 0.04 Published 1978 Journal Brain Res. Section Abstract Doc Link 638765 Disease Relevance 0.37 Pain Relevance 0.23

General Comments

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