INT313292

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (SQSTM1, NFE2L2) cytosol (SQSTM1, NFE2L2) nucleus (SQSTM1, NFE2L2)
cell differentiation (SQSTM1) nucleoplasm (SQSTM1) DNA binding (NFE2L2)
SQSTM1 (Homo sapiens)
NFE2L2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuroblastoma 1 87.24 High High
Repression 1 44.88 Quite Low
Stress 7 11.28 Low Low
Bone Disease 3 5.00 Very Low Very Low Very Low
Adenocarcinoma 2 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Spontaneous Fractures 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, we have demonstrated that the ability of SQSTM1 to regulate the basal protein level of Nrf2 is also due to its capacity to alter the basal protein level of Keap1, by affecting its rate of degradation.
Positive_regulation (due) of SQSTM1 Regulation (regulate) of Nrf2
1) Confidence 0.26 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2878012 Disease Relevance 0.09 Pain Relevance 0

General Comments

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