INT313306

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (KEAP1, SPARC) nucleus (KEAP1, SPARC) endoplasmic reticulum (KEAP1)
intracellular (SPARC) signal transduction (SPARC) extracellular space (SPARC)
KEAP1 (Homo sapiens)
SPARC (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 7 99.22 Very High Very High Very High
Targeted Disruption 1 95.92 Very High Very High Very High
Toxicity 1 95.36 Very High Very High Very High
Bone Disease 3 5.00 Very Low Very Low Very Low
Adenocarcinoma 2 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Neuroblastoma 1 5.00 Very Low Very Low Very Low
Repression 1 5.00 Very Low Very Low Very Low
Spontaneous Fractures 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the absence of chemical/oxidative stress, the activity of Nrf2 is repressed by Keap1, a cysteine-rich protein that acts as a substrate adaptor for the cullin 3-dependent ubiquitination of Nrf2, thereby directing the transcription factor for proteasomal degradation (5–7).
Keap1 Positive_regulation (acts) of cysteine-rich protein associated with stress
1) Confidence 0.02 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2878012 Disease Relevance 0.37 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox