INT313307

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (TERT, NFE2L2) cytoplasm (TERT, NFE2L2) nucleus (TERT, NFE2L2)
nucleoplasm (TERT) cytosol (NFE2L2) RNA binding (TERT)
TERT (Homo sapiens)
NFE2L2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 7 5.00 Very Low Very Low Very Low
Bone Disease 3 5.00 Very Low Very Low Very Low
Adenocarcinoma 2 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Neuroblastoma 1 5.00 Very Low Very Low Very Low
Repression 1 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Spontaneous Fractures 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SQSTM1 was dispensable for the induction of the Keap1-Nrf2 pathway, as Nrf2 activation by tert-butylhydroquinone or iodoacetamide was not affected by RNAi depletion of SQSTM1.
tert-butylhydroquinone Positive_regulation (activation) of Nrf2
1) Confidence 0.01 Published 2010 Journal The Journal of Biological Chemistry Section Abstract Doc Link PMC2878012 Disease Relevance 0 Pain Relevance 0

General Comments

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