INT313380

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Context Info
Confidence 0.36
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cnr1, Trpv1) transport (Trpv1) aging (Cnr1)
transmembrane transport (Trpv1) lipid metabolic process (Trpv1) response to stress (Cnr1)
Anatomy Link Frequency
paw 1
Cnr1 (Rattus norvegicus)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 16 100.00 Very High Very High Very High
Opioid 1 98.92 Very High Very High Very High
agonist 10 97.80 Very High Very High Very High
Endocannabinoid 25 50.00 Quite Low
allodynia 19 33.04 Quite Low
withdrawal 13 20.08 Low Low
Perioperative pain 21 5.00 Very Low Very Low Very Low
Spinal cord 20 5.00 Very Low Very Low Very Low
Cannabinoid receptor 15 5.00 Very Low Very Low Very Low
Lasting pain 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 17 89.92 High High
Neuropathic Pain 25 33.04 Quite Low
Post Operative Pain 22 5.00 Very Low Very Low Very Low
Pain 21 5.00 Very Low Very Low Very Low
INFLAMMATION 13 5.00 Very Low Very Low Very Low
Nociception 8 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 6 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although some studies indicate that CB1 receptor antagonists may interact with TRPV1 channels [55] or with the opioid system via prodynorphin production [49], it is unlikely that our behavioral findings were influenced by interactions between our antagonist treatment and these systems, which do not play a role in paw-incision-induced hypersensitivity [56], [57].
CB1 receptor Binding (interact) of TRPV1 in paw associated with antagonist, hypersensitivity and opioid
1) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2878341 Disease Relevance 0.09 Pain Relevance 0.39

General Comments

This test has worked.

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