INT313393

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Context Info
Confidence 0.29
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cnr2) signal transducer activity (Cnr2)
Cnr2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hyperalgesia 2 76.24 Quite High
agonist 36 70.52 Quite High
Nerve growth factor 1 66.48 Quite High
Pain 21 52.16 Quite High
Spinal cord 2 50.88 Quite High
Cannabinoid receptor 15 50.00 Quite Low
antagonist 9 39.00 Quite Low
Cannabinoid 46 16.64 Low Low
cannabis 13 5.00 Very Low Very Low Very Low
Endocannabinoid 11 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cystitis 1 85.12 High High
Overactive Bladder 25 78.32 Quite High
Hyperalgesia 2 76.24 Quite High
Pain 25 52.16 Quite High
Nociception 11 5.00 Very Low Very Low Very Low
Interstitial Cystitis 8 5.00 Very Low Very Low Very Low
Bladder Disease 8 5.00 Very Low Very Low Very Low
Neuropathic Pain 6 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Vomiting 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The pre-synaptic inhibitory effect of anandamide is evident at low concentration and at higher concentrations the activation of TRPV1 counters the effect on CB1/CB2 receptors.[19] The activation of TRPV1 channels can lead to desensitization and loss of pre-synaptic inhibition observed in various studies.[28]
Regulation (effect) of Positive_regulation (activation) of CB2
1) Confidence 0.29 Published 2010 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2878434 Disease Relevance 0.59 Pain Relevance 0.28

General Comments

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