INT313454

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Context Info
Confidence 0.30
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Th) mitochondrion (Th) transport (Syp)
oxidoreductase activity (Th) nucleus (Th) protein complex (Syp)
Syp (Mus musculus)
Th (Mus musculus)
Pain Link Frequency Relevance Heat
Catecholamine 6 78.20 Quite High
Dopamine 20 53.56 Quite High
Substantia nigra 9 5.00 Very Low Very Low Very Low
midbrain 4 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Tetrahydrobiopterin 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 10 86.96 High High
Parkinson's Disease 18 52.00 Quite High
Apoptosis 3 5.00 Very Low Very Low Very Low
Aging 3 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Phosphorylation of a-Syn Ser-129 by Polo-like-kinase 2 in vitro reduced the ability of a-Syn to inhibit TH or activate PP2A, identifying a novel regulatory role for Ser-129 on a-Syn.
Negative_regulation (reduced) of Syn Negative_regulation (inhibit) of TH
1) Confidence 0.30 Published 2010 Journal The Journal of Biological Chemistry Section Abstract Doc Link PMC2878529 Disease Relevance 0.14 Pain Relevance 0.10

General Comments

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