INT313506

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (SNRNP70) extracellular space (ICAM1) mRNA processing (SNRNP70)
RNA binding (SNRNP70) cell adhesion (ICAM1) nucleus (SNRNP70)
ICAM1 (Homo sapiens)
SNRNP70 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 26 71.12 Quite High
aspirin 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Calcification 24 92.00 High High
INFLAMMATION 26 71.12 Quite High
Atherosclerosis 86 66.36 Quite High
Diabetes Mellitus 54 50.00 Quite Low
Cardiovascular Disease 22 5.00 Very Low Very Low Very Low
Myocardial Infarction 8 5.00 Very Low Very Low Very Low
Nicotine Addiction 6 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 6 5.00 Very Low Very Low Very Low
Atherosclerotic Plaque 4 5.00 Very Low Very Low Very Low
Stroke 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ALOX12 SNP also was associated with CRP level (P = .036), but also significantly associated with ICAM-1 level (P = .032) in a recessive pattern [rs2271316 GG (295.7), GC (268.3), CC (266.0)].
ICAM-1 Binding (associated) of SNP
1) Confidence 0.02 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2878676 Disease Relevance 0.54 Pain Relevance 0.03
This SNP was also associated with ICAM-1 (P = .037) and E-selectin (P = .0001); however, the genotypic means did not fit a classical single gene model, as the levels of both ICAM-1 and E-selectin for the heterozygote (T/C) class were greater than the means for the homozygote classes.
ICAM-1 Binding (associated) of SNP
2) Confidence 0.02 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2878676 Disease Relevance 0.54 Pain Relevance 0.04

General Comments

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