INT313627

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Grin2d) plasma membrane (Grin2d)
Anatomy Link Frequency
lamina 1
Grin2d (Mus musculus)
Pain Link Frequency Relevance Heat
nMDA receptor 79 99.96 Very High Very High Very High
GABAergic 14 97.52 Very High Very High Very High
Glutamate 7 90.56 High High
Dorsal horn 13 82.68 Quite High
Neuropathic pain 1 79.60 Quite High
Inflammation 2 70.36 Quite High
Pain 5 66.72 Quite High
isoflurane 1 38.88 Quite Low
gABA 1 14.40 Low Low
nMDA receptor antagonist 2 12.84 Low Low
Disease Link Frequency Relevance Heat
Nervous System Injury 3 84.68 Quite High
Apoptosis 1 81.68 Quite High
Neuropathic Pain 5 79.60 Quite High
Death 2 77.12 Quite High
INFLAMMATION 2 70.36 Quite High
Injury 1 69.72 Quite High
Pain 5 66.72 Quite High
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 3 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, we demonstrated that NR2A and NR2B containing receptors with high Mg2+ sensitivity and NR2D containing NMDA receptors with low Mg2+ sensitive are both expressed on GABAergic lamina II interneurons.
NR2D Binding (containing) of in lamina associated with gabaergic and nmda receptor
1) Confidence 0.26 Published 2010 Journal Mol Pain Section Body Doc Link PMC2879240 Disease Relevance 0.60 Pain Relevance 0.85

General Comments

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