INT313701

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Context Info
Confidence 0.30
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Calca, Edn1) extracellular region (Calca, Edn1) cytoplasm (Calca, Edn1)
aging (Calca) nucleus (Calca) intracellular (Calca)
Anatomy Link Frequency
smooth muscle 2
Calca (Rattus norvegicus)
Edn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 39 100.00 Very High Very High Very High
qutenza 14 99.56 Very High Very High Very High
agonist 22 98.16 Very High Very High Very High
antagonist 41 82.56 Quite High
Potency 3 55.96 Quite High
Neurotransmitter 4 13.28 Low Low
Inflammation 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
TRP channel 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 3 77.92 Quite High
Disease 4 57.52 Quite High
Hypertension 1 34.24 Quite Low
Cardiovascular Disease 3 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, capsaicin (1 µM) and exogenous CGRP (100 nM; investigated in presence and absence (not shown) of 1 µM BQ788), reversed the binding of Rh-ET-1 to smooth muscle that remained after exposure to Rh-ET-1 (Fig. 6I/M).
CGRP Negative_regulation (reversed) of Rh-ET-1 Binding (binding) of in smooth muscle associated with qutenza and calcitonin gene-related peptide
1) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2879375 Disease Relevance 0.14 Pain Relevance 0.37

General Comments

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