INT313778

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crh) extracellular region (Crh) response to stress (Crh)
cytoplasm (Crh)
Anatomy Link Frequency
enteric nervous system 3
Crhq1 (Mus musculus)
Crh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
spastic colon 196 100.00 Very High Very High Very High
lidocaine 1 95.64 Very High Very High Very High
antagonist 2 65.56 Quite High
abdominal pain 13 54.60 Quite High
nud 9 31.92 Quite Low
depression 1 5.00 Very Low Very Low Very Low
Cholecystokinin 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
colic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

194 100.00 Very High Very High Very High
Stress 23 79.32 Quite High
Abdominal Pain 13 54.60 Quite High
Dyspepsia 9 31.92 Quite Low
Brain Disease 1 28.60 Quite Low
Diarrhoea 35 5.00 Very Low Very Low Very Low
Constipation 28 5.00 Very Low Very Low Very Low
Functional Bowel Disorder 4 5.00 Very Low Very Low Very Low
Gastric Motility Disorder 4 5.00 Very Low Very Low Very Low
Vomiting 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-helical CRH clearly decreases colonic motility in IBS patients, probably by antagonizing CRH1 in the enteric nervous system.100
Gene_expression (antagonizing) of CRH1 in enteric nervous system Negative_regulation (decreases) of Localization (helical) of CRH in enteric nervous system associated with spastic colon
1) Confidence 0.05 Published 2010 Journal Journal of Neurogastroenterology and Motility Section Body Doc Link PMC2879849 Disease Relevance 0.13 Pain Relevance 0.71

General Comments

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