INT313840

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Acvr2b, Mstn) extracellular space (Mstn) signal transduction (Acvr2b)
growth (Mstn) extracellular region (Mstn) plasma membrane (Acvr2b)
Anatomy Link Frequency
muscle 1
Acvr2b (Rattus norvegicus)
Mstn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metabolic Disorder 3 72.96 Quite High
Body Weight 3 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low
Obesity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The binding of the myostatin dimer to its receptor (ActRIIB) initiates the Smad mediated signaling pathway, which results in the transcription and expression of genes needed to mediate the negative regulation of muscle development.
ActRIIB Binding (binding) of myostatin in muscle
1) Confidence 0.02 Published 2010 Journal Nutr Metab (Lond) Section Body Doc Link PMC2880107 Disease Relevance 0.07 Pain Relevance 0

General Comments

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