INT31388

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Context Info
Confidence 0.45
First Reported 1987
Last Reported 2006
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.55
Pain Relevance 1.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (PRCP) plasma membrane (PRCP) lysosome (PRCP)
Anatomy Link Frequency
neural 1
PRCP (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 5 99.54 Very High Very High Very High
opiate 9 99.04 Very High Very High Very High
cannabis 16 93.84 High High
narcan 8 92.20 High High
agonist 4 91.92 High High
antagonist 4 89.04 High High
cocaine 28 84.28 Quite High
drug abuse 57 82.44 Quite High
addiction 3 50.36 Quite High
alcohol 4 49.92 Quite Low
Disease Link Frequency Relevance Heat
Psychosis 2 94.00 High High
Death 5 87.48 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 83.24 Quite High
Drug Dependence 58 82.44 Quite High
Phencyclidine Abuse 4 82.16 Quite High
Alcohol Addiction 2 50.36 Quite High
Adverse Drug Reaction 3 47.72 Quite Low
Disease 3 13.36 Low Low
Cardiovascular Disease 9 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have investigated whether PCP receptor binding parameters are modulated by activity in central opiate pathways.
Spec (whether) Regulation (modulated) of PCP associated with opiate
1) Confidence 0.45 Published 1987 Journal Neuropeptides Section Abstract Doc Link 2891074 Disease Relevance 0.09 Pain Relevance 0.67
These results suggest that neural activity mediated by CNS opioids systems is capable of affecting the binding parameters of the PCP receptor.
Regulation (affecting) of PCP in neural associated with opioid
2) Confidence 0.33 Published 1987 Journal Neuropeptides Section Abstract Doc Link 2891074 Disease Relevance 0.07 Pain Relevance 0.68
A total of 964, 299 and 1152 transcripts were exclusively changed in the COC+, THC+ and PCP+ groups, respectively.
Regulation (changed) of PCP
3) Confidence 0.15 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762434 Disease Relevance 0.30 Pain Relevance 0.41
The community pharmacists can then change the patient's PCP accordingly and avoid drug-related problems arising from miscommunication after hospital discharge.
Regulation (change) of PCP
4) Confidence 0.12 Published 2004 Journal BMC Health Serv Res Section Body Doc Link PMC441396 Disease Relevance 0.08 Pain Relevance 0

General Comments

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