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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (XRCC1, PTEN) nucleoplasm (XRCC1) intracellular (XRCC1)
enzyme binding (PTEN) lipid metabolic process (PTEN) cytoplasm (PTEN)
XRCC1 (Homo sapiens)
PTEN (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 3 47.92 Quite Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Renal Cancer 27 100.00 Very High Very High Very High
Disease 19 94.58 High High
Cancer 8 93.08 High High
Metastasis 4 74.20 Quite High
Toxicity 10 48.96 Quite Low
Disease Progression 6 46.32 Quite Low
Pneumonia 12 5.00 Very Low Very Low Very Low
Hypoxia 3 5.00 Very Low Very Low Very Low
Stomatitis 3 5.00 Very Low Very Low Very Low
Vomiting 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A substantial study of 375 patients investigated the prognostic significance of mTOR pathway components in tumors obtained at nephrectomy, and observed adverse prognostic impact on disease-specific survival of pS6K, PTEN and Akt independent of stage.73 A small study further suggested that pS6K and possibly Akt were predictors of response to temsirolimus for advanced RCC.67,74 However an extension of the study20 of temsirolimus for poor prognosis advanced RCC did not find a correlation between PTEN and HIF-1?
RCC Neg (not) Spec (find) Positive_regulation (find) of Localization (correlation) of PTEN associated with cancer, renal cancer and disease
1) Confidence 0.00 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2880340 Disease Relevance 0.65 Pain Relevance 0

General Comments

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