INT314051

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Context Info
Confidence 0.14
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.10
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp2) extracellular space (Mmp2) extracellular region (Mmp2)
proteinaceous extracellular matrix (Mmp2) plasma membrane (Mmp2) nucleus (Mmp2)
Anatomy Link Frequency
endothelial cells 2
THL (Mus musculus)
Mmp2 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 62 100.00 Very High Very High Very High
Potency 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 314 99.20 Very High Very High Very High
Metastasis 66 99.00 Very High Very High Very High
Breast Cancer 18 60.64 Quite High
Wound Healing 6 36.92 Quite Low
Recurrence 2 36.56 Quite Low
Colon Cancer 16 13.40 Low Low
Lung Cancer 4 11.88 Low Low
Prostate Cancer 4 8.96 Low Low
Severe Combined Immunodeficiency 18 5.00 Very Low Very Low Very Low
Hypoxia 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We thus tested whether THL could inhibit the secretion of MMP-2 and uPA in endothelial cells.
THL Negative_regulation (inhibit) of Localization (secretion) of MMP-2 in endothelial cells associated with metalloproteinase
1) Confidence 0.14 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2880989 Disease Relevance 0.14 Pain Relevance 0.22
We thus tested whether THL could inhibit the secretion of MMP-2, MMP-9, and uPA in cancer cells.
THL Negative_regulation (inhibit) of Localization (secretion) of MMP-2 associated with cancer and metalloproteinase
2) Confidence 0.14 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2880989 Disease Relevance 0.95 Pain Relevance 0.39

General Comments

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