INT314052

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.25
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (VEGFA, Sp1) intracellular (Sp1) DNA binding (Sp1)
extracellular space (VEGFA) extracellular region (VEGFA) growth (VEGFA)
VEGFA (Homo sapiens)
Sp1 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 31 66.36 Quite High
Potency 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 157 97.88 Very High Very High Very High
Hypoxia 7 88.96 High High
Metastasis 33 50.00 Quite Low
Severe Combined Immunodeficiency 9 42.68 Quite Low
Breast Cancer 9 5.00 Very Low Very Low Very Low
Colon Cancer 8 5.00 Very Low Very Low Very Low
Injury 7 5.00 Very Low Very Low Very Low
Apoptosis 7 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Secondly, we found that THL could inhibit, in cancer cells, the activity of ERK1/2 (Fig 2D), which phosphorylates the transcription factor Sp1 and causes the recruitment of Sp1 to the vegf-A promoter [65].
vegf Binding (recruitment) of Sp1 associated with cancer
1) Confidence 0.02 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2880989 Disease Relevance 1.25 Pain Relevance 0.03

General Comments

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