INT314060

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Context Info
Confidence 0.38
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Stat1) nucleus (Stat1) enzyme binding (Stat1)
DNA binding (Stat1) cytoplasm (Stat1)
Stat1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 28 50.00 Quite Low
chemokine 3 49.56 Quite Low
cytokine 11 46.56 Quite Low
Crohn's disease 4 5.00 Very Low Very Low Very Low
Piles 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Inflammatory Bowel Disease 38 84.16 Quite High
Colitis 19 65.60 Quite High
Disease 15 64.96 Quite High
INFLAMMATION 27 50.00 Quite Low
Body Weight 5 5.00 Very Low Very Low Very Low
Cancer 5 5.00 Very Low Very Low Very Low
Hemorrhage 5 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Diarrhoea 2 5.00 Very Low Very Low Very Low
Anorectal Disorders 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Based on our current observations we hypothesize that the decrease in nuclear pSTAT1 is primarily due to lower levels cytoplasmic STAT1 protein (Fig 5) that serves as the kinase substrate before translocation.
Positive_regulation (due) of Negative_regulation (decrease) of pSTAT1
1) Confidence 0.38 Published 2010 Journal BMC Chem Biol Section Body Doc Link PMC2881005 Disease Relevance 0.29 Pain Relevance 0

General Comments

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