INT314075

Context Info Confidence 0.37 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.43 Pain Relevance 0.08

mitochondrion (Peo1) nucleolus (Stat1) nucleus (Stat1) helicase activity (Peo1) enzyme binding (Stat1) DNA binding (Stat1)

Peo1 (Mus musculus) Stat1 (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 28 93.24 Inflammatory mediators 1 58.60 agonist 1 40.48 cytokine 11 11.44 Crohn's disease 4 5.00 chemokine 3 5.00 Piles 2 5.00 aspirin 1 5.00 cINOD 1 5.00 Bioavailability 1 5.00

Disease Link Frequency Relevance Heat Inflammatory Bowel Disease 38 94.12 Disease 15 93.60 INFLAMMATION 27 93.24 Colitis 19 43.36 Body Weight 5 5.00 Cancer 5 5.00 Hemorrhage 5 5.00 Toxicity 2 5.00 Diarrhoea 2 5.00 Anorectal Disorders 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

But since activity of PEITC on STAT3 activation is known [26], our subsequent investigation focused on effects of PEO on STAT1 activation and expression.

PEO Regulation (effects) of Positive_regulation (activation) of STAT1

1) Confidence 0.37 Published 2010 Journal BMC Chem Biol Section Body Doc Link PMC2881005 Disease Relevance 0.43 Pain Relevance 0.08

General Comments

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