INT314134

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Context Info
Confidence 0.36
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Ucp3) mitochondrion (Ucp3) peroxisome (Nos2)
intracellular (Nos2) transmembrane transport (Ucp3) cytoplasm (Nos2)
Nos2 (Mus musculus)
Ucp3 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 3 96.96 Very High Very High Very High
Eae 7 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 119 87.56 High High
Targeted Disruption 40 70.76 Quite High
Infection 3 35.44 Quite Low
Cv General 2 Under Development 2 12.72 Low Low
Body Weight 23 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Insulin Resistance 4 5.00 Very Low Very Low Very Low
Impaired Glucose Tolerance 2 5.00 Very Low Very Low Very Low
Hyperphagia 2 5.00 Very Low Very Low Very Low
Fever 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this sense, levels of UCP-3 were reduced in the absence of leptin and were significantly upregulated by the deficiency of the iNOS gene.
Negative_regulation (deficiency) of iNOS Positive_regulation (upregulated) of UCP-3
1) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2881035 Disease Relevance 0.45 Pain Relevance 0.05

General Comments

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