INT314142

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TAC1, Tacr3) signal transduction (Tacr3) extracellular space (TAC1)
extracellular region (TAC1) nucleus (Tacr3) signal transducer activity (Tacr3)
Anatomy Link Frequency
skin 1
TAC1 (Homo sapiens)
Tacr3 (Mus musculus)
Pain Link Frequency Relevance Heat
substance P 21 99.88 Very High Very High Very High
Central nervous system 5 98.88 Very High Very High Very High
pruritus 71 96.24 Very High Very High Very High
Potency 1 87.44 High High
antagonist 12 83.92 Quite High
Opioid 1 80.52 Quite High
Pain 12 67.44 Quite High
antidepressant 2 61.92 Quite High
corticosteroid 4 61.12 Quite High
Antihistamine 4 55.12 Quite High
Disease Link Frequency Relevance Heat
Pruritus 82 96.24 Very High Very High Very High
Disease 6 70.12 Quite High
Pain 12 67.44 Quite High
Suicidal Behaviour 1 36.36 Quite Low
Depression 3 35.72 Quite Low
Injury 1 32.12 Quite Low
Chronic Renal Failure 4 17.36 Low Low
Uremia 3 15.44 Low Low
Diabetes Mellitus 1 7.76 Low Low
Hyperuricemia 1 6.24 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SP is a tachykinin which binds with different affinities to three neurokinin receptors (NKR 1–3), but mainly to NKR1, which is expressed in the central nervous system (CNS) and the skin [11].
tachykinin Binding (binds) of NKR1 in skin associated with central nervous system and substance p
1) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2881044 Disease Relevance 0.73 Pain Relevance 0.94

General Comments

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