INT314147

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp1a) extracellular region (Mmp1a) proteinaceous extracellular matrix (Mmp1a)
Anatomy Link Frequency
fibroblasts 2
Mmp1a (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 47 97.28 Very High Very High Very High
Inflammation 40 89.04 High High
Inflammatory response 5 84.04 Quite High
cytokine 7 47.96 Quite Low
Inflammatory marker 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Fibrosis 28 97.28 Very High Very High Very High
INFLAMMATION 42 89.04 High High
Pulmonary Disease 3 88.04 High High
Colitis 1 77.04 Quite High
Disease 4 58.80 Quite High
Interstitial Lung Diseases 1 34.92 Quite Low
Fibrosis 20 5.00 Very Low Very Low Very Low
Pneumonia 7 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PDE4 inhibitor cilomilast was also shown to suppress the release and activation of MMP-1 and MMP-9 from lung fibroblasts, which are known to be involved in PF progression [18].
Negative_regulation (suppress) of Localization (release) of MMP-1 in fibroblasts associated with fibrosis
1) Confidence 0.15 Published 2010 Journal BMC Pulm Med Section Body Doc Link PMC2881047 Disease Relevance 0.72 Pain Relevance 0.25

General Comments

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