INT314189

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 2.16
Pain Relevance 1.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Nr5a1) lipid binding (Nr5a1) nucleus (Nr5a1)
enzyme binding (Nr5a1) DNA binding (Nr5a1)
Anatomy Link Frequency
dorsal root 1
neurons 1
Nr5a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Nerve growth factor 45 100.00 Very High Very High Very High
Trk A 11 100.00 Very High Very High Very High
Hyperalgesia 6 99.82 Very High Very High Very High
Inflammation 15 95.52 Very High Very High Very High
Pain 17 91.24 High High
Spinal cord 6 90.16 High High
Neuropathic pain 4 88.16 High High
Painful diabetic neuropathy 27 74.88 Quite High
allodynia 39 60.16 Quite High
tolerance 1 54.04 Quite High
Disease Link Frequency Relevance Heat
Nociception 6 99.84 Very High Very High Very High
Hyperalgesia 7 99.82 Very High Very High Very High
INFLAMMATION 23 95.52 Very High Very High Very High
Pain 15 91.24 High High
Neuropathic Pain 48 88.16 High High
Diabetic Neuropathy 36 74.88 Quite High
Diabetes Mellitus 44 70.64 Quite High
Impaired Glucose Tolerance 1 54.04 Quite High
Disease 2 45.36 Quite Low
Neuropathy 1 36.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a model of NGF-induced hyperalgesia, p38 is phosphorylated in Trk A-positive small to medium-sized dorsal root ganglian (DRG) neurons and phosphorylated p38 (pp38) mediates NGF-induced upregulation of nociceptive molecules [10].
Positive_regulation (upregulation) of in neurons Phosphorylation (phosphorylated) of A-positive in dorsal root associated with nociception, hyperalgesia, nerve growth factor and trk a
1) Confidence 0.02 Published 2010 Journal Mol Pain Section Body Doc Link PMC2881061 Disease Relevance 2.16 Pain Relevance 1.70

General Comments

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