INT314208

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Trap1, Mapk14) response to stress (Trap1, Mapk14) unfolded protein binding (Trap1)
cell morphogenesis (Mapk14) cytoplasm (Mapk14) cytosol (Mapk14)
Trap1 (Mus musculus)
Mapk14 (Mus musculus)
Pain Link Frequency Relevance Heat
tetrodotoxin 1 99.32 Very High Very High Very High
sodium channel 1 98.40 Very High Very High Very High
Nerve growth factor 45 88.84 High High
Pain 17 82.16 Quite High
Inflammation 15 81.80 Quite High
COX2 29 67.84 Quite High
Hyperalgesia 6 63.68 Quite High
intrathecal 10 60.00 Quite High
allodynia 39 50.00 Quite Low
Painful diabetic neuropathy 27 45.08 Quite Low
Disease Link Frequency Relevance Heat
Nociception 6 99.86 Very High Very High Very High
Nervous System Injury 3 96.80 Very High Very High Very High
Pain 15 82.16 Quite High
INFLAMMATION 23 81.80 Quite High
Diabetes Mellitus 44 64.92 Quite High
Hyperalgesia 7 63.68 Quite High
Neuropathic Pain 48 50.00 Quite Low
Diabetic Neuropathy 36 45.08 Quite Low
Targeted Disruption 1 36.60 Quite Low
Hyperglycemia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
could increase mechanical nociception is by activating p38 via the TNF receptor 1 to modulate the tetrodotoxin-resistant sodium channel in DRG [50].
TNF receptor 1 Positive_regulation (activating) of p38 associated with nociception, tetrodotoxin and sodium channel
1) Confidence 0.10 Published 2010 Journal Mol Pain Section Body Doc Link PMC2881061 Disease Relevance 0.66 Pain Relevance 0.57

General Comments

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