INT314214

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Context Info
Confidence 0.43
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.97
Pain Relevance 1.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Mapk14) cell morphogenesis (Mapk14) response to stress (Mapk14)
cytoplasm (Mapk14) cytosol (Mapk14) signal transduction (Ngf)
Anatomy Link Frequency
neurons 1
Mapk14 (Mus musculus)
Ngf (Mus musculus)
Pain Link Frequency Relevance Heat
Nerve growth factor 45 100.00 Very High Very High Very High
Trk A 11 98.28 Very High Very High Very High
Hyperalgesia 6 97.64 Very High Very High Very High
Inflammation 15 93.84 High High
Spinal cord 6 88.48 High High
Pain 17 86.88 High High
Neuropathic pain 4 83.80 Quite High
Painful diabetic neuropathy 27 73.20 Quite High
allodynia 39 55.80 Quite High
tolerance 1 49.68 Quite Low
Disease Link Frequency Relevance Heat
Nociception 6 99.00 Very High Very High Very High
Hyperalgesia 7 97.64 Very High Very High Very High
INFLAMMATION 23 93.84 High High
Pain 15 86.88 High High
Neuropathic Pain 48 83.80 Quite High
Diabetic Neuropathy 36 73.20 Quite High
Diabetes Mellitus 44 68.96 Quite High
Impaired Glucose Tolerance 1 49.68 Quite Low
Disease 2 43.68 Quite Low
Neuropathy 1 31.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a model of NGF-induced hyperalgesia, p38 is phosphorylated in Trk A-positive small to medium-sized dorsal root ganglian (DRG) neurons and phosphorylated p38 (pp38) mediates NGF-induced upregulation of nociceptive molecules [10].
p38 Positive_regulation (mediates) of NGF in neurons associated with nociception, hyperalgesia, nerve growth factor and trk a
1) Confidence 0.43 Published 2010 Journal Mol Pain Section Body Doc Link PMC2881061 Disease Relevance 1.97 Pain Relevance 1.56

General Comments

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