INT314267

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CPOX, PTGES) isomerase activity (PTGES) signal transduction (PTGES)
mitochondrion (CPOX) small molecule metabolic process (CPOX) oxidoreductase activity (CPOX)
CPOX (Homo sapiens)
PTGES (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 2 63.08 Quite High
Inflammation 10 59.68 Quite High
COX-2 inhibitor 3 5.00 Very Low Very Low Very Low
melanocortin 1 receptor 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Erythema 9 90.08 High High
Stress 5 76.52 Quite High
INFLAMMATION 11 62.68 Quite High
Blister 2 36.92 Quite Low
Increased Venous Pressure Under Development 2 28.88 Quite Low
Burns 5 5.00 Very Low Very Low Very Low
Skin Cancer 4 5.00 Very Low Very Low Very Low
Dermatitis 1 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Three isoforms of PGES have been described; two with preferential coupling to the two COX pathways (cPGES couples preferentially to COX-1 and mPGES-1 to COX-2, while mPGES-2 shows little preference for either pathway) (Murakami et al., 2003).
COX Binding (couples) of mPGES-1
1) Confidence 0.03 Published 2010 Journal Pigment Cell & Melanoma Research Section Body Doc Link PMC2881306 Disease Relevance 0.34 Pain Relevance 0.09

General Comments

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