INT314369

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.20
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Tnfsf11, Tnfrsf11b) cell differentiation (Tnfsf11) intracellular (Tnfsf11)
extracellular matrix organization (Tnfrsf11b) cytoplasm (Tnfsf11) extracellular space (Tnfsf11)
Anatomy Link Frequency
osteoblasts 4
Tnfsf11 (Mus musculus)
Tnfrsf11b (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 4 53.08 Quite High
Inflammation 10 5.00 Very Low Very Low Very Low
imagery 8 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 2 95.76 Very High Very High Very High
Obesity 24 94.00 High High
Solid Tumor 2 92.40 High High
Metastasis 4 91.76 High High
Bone Cancer 12 89.68 High High
Cancer 152 83.44 Quite High
Osteogenic Sarcomas 128 72.68 Quite High
Breast Cancer 12 44.48 Quite Low
Recurrence 54 23.36 Low Low
Osteoporosis 4 23.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B Ligand (RANKL or TNFSF11) and inhibit Osteoprotegerin expression in osteoblasts [29].
RANKL Negative_regulation (inhibit) of Gene_expression (expression) of Osteoprotegerin in osteoblasts
1) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2882323 Disease Relevance 1.10 Pain Relevance 0.03
B Ligand (RANKL or TNFSF11) and inhibit Osteoprotegerin expression in osteoblasts [29].
TNFSF11 Negative_regulation (inhibit) of Gene_expression (expression) of Osteoprotegerin in osteoblasts
2) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2882323 Disease Relevance 1.10 Pain Relevance 0.03

General Comments

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