INT31438

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Context Info
Confidence 0.18
First Reported 1987
Last Reported 1987
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 1.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Penk, Pomc) signal transduction (Pomc) generation of precursor metabolites and energy (Pomc)
extracellular space (Pomc) molecular_function (Pomc) cell-cell signaling (Pomc)
Penk (Rattus norvegicus)
Pomc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 12 100.00 Very High Very High Very High
Enkephalin 3 100.00 Very High Very High Very High
Dynorphin 12 99.94 Very High Very High Very High
agonist 6 75.00 Quite High
opiate 3 75.00 Quite High
Analgesic 3 25.00 Low Low
Opioid 3 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Diurnal variations of the effectivity of beta-endorphin (beta-End), dynorphin (DYN), Met-enkephalin (Met-Enk), D-Met2-Pro5-enkephalinamide (D-Met-Pro-Enk) and morphine to induce prolactin (PRL) and adrenocorticotropin (ACTH)/corticosterone (CS) release in intact and adrenalectomized rats have been examined.
Enk Positive_regulation (induce) of Localization (release) of adrenocorticotropin associated with dynorphin, enkephalin and morphine
1) Confidence 0.18 Published 1987 Journal Neuroendocrinology Section Abstract Doc Link 2892145 Disease Relevance 0 Pain Relevance 0.63
Diurnal variations of the effectivity of beta-endorphin (beta-End), dynorphin (DYN), Met-enkephalin (Met-Enk), D-Met2-Pro5-enkephalinamide (D-Met-Pro-Enk) and morphine to induce prolactin (PRL) and adrenocorticotropin (ACTH)/corticosterone (CS) release in intact and adrenalectomized rats have been examined.
Enk Positive_regulation (induce) of Localization (release) of adrenocorticotropin associated with dynorphin, enkephalin and morphine
2) Confidence 0.18 Published 1987 Journal Neuroendocrinology Section Abstract Doc Link 2892145 Disease Relevance 0 Pain Relevance 0.63
Diurnal variations of the effectivity of beta-endorphin (beta-End), dynorphin (DYN), Met-enkephalin (Met-Enk), D-Met2-Pro5-enkephalinamide (D-Met-Pro-Enk) and morphine to induce prolactin (PRL) and adrenocorticotropin (ACTH)/corticosterone (CS) release in intact and adrenalectomized rats have been examined.
Met-enkephalin Positive_regulation (induce) of Localization (release) of adrenocorticotropin associated with dynorphin, enkephalin and morphine
3) Confidence 0.05 Published 1987 Journal Neuroendocrinology Section Abstract Doc Link 2892145 Disease Relevance 0 Pain Relevance 0.63

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