INT31443

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Context Info
Confidence 0.00
First Reported 1987
Last Reported 1987
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.63

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cytoplasm (ENG, Pomc) extracellular space (ENG, Pomc) cell-cell signaling (Pomc)
signal transduction (Pomc) generation of precursor metabolites and energy (Pomc) extracellular region (Pomc)
ENG (Homo sapiens)
Pomc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dynorphin 4 100.00 Very High Very High Very High
Morphine 4 100.00 Very High Very High Very High
Enkephalin 1 100.00 Very High Very High Very High
agonist 2 75.00 Quite High
opiate 1 75.00 Quite High
Analgesic 1 25.00 Low Low
Opioid 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Diurnal variations of the effectivity of beta-endorphin (beta-End), dynorphin (DYN), Met-enkephalin (Met-Enk), D-Met2-Pro5-enkephalinamide (D-Met-Pro-Enk) and morphine to induce prolactin (PRL) and adrenocorticotropin (ACTH)/corticosterone (CS) release in intact and adrenalectomized rats have been examined.
beta-End Positive_regulation (induce) of Localization (release) of adrenocorticotropin associated with dynorphin, enkephalin and morphine
1) Confidence 0.00 Published 1987 Journal Neuroendocrinology Section Abstract Doc Link 2892145 Disease Relevance 0 Pain Relevance 0.63

General Comments

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