INT314537

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Context Info
Confidence 0.21
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 1.23
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il10) extracellular region (Il10) cell adhesion (Itgam)
nucleus (Itgam) intracellular (Il10)
Anatomy Link Frequency
macrophages 3
phagocytes 2
neutrophils 1
Il10 (Mus musculus)
Itgam (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 42 5.00 Very Low Very Low Very Low
Inflammation 27 5.00 Very Low Very Low Very Low
Inflammatory response 27 5.00 Very Low Very Low Very Low
imagery 12 5.00 Very Low Very Low Very Low
cerebral cortex 6 5.00 Very Low Very Low Very Low
dexamethasone 6 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
withdrawal 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
psoriasis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 3 94.20 High High
Apoptosis 57 92.68 High High
Bacteremia 39 86.80 High High
Meningitis 111 86.48 High High
Sprains And Strains 21 81.60 Quite High
Infection 186 77.60 Quite High
INFLAMMATION 63 5.00 Very Low Very Low Very Low
Sepsis 24 5.00 Very Low Very Low Very Low
Injury 15 5.00 Very Low Very Low Very Low
Disease 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This indicates that rh-IL-10 enhances CR3 expression so that the bacteria enter through CR3 for efficient destruction by phagocytes.


rh-IL-10 Positive_regulation (enhances) of Gene_expression (expression) of CR3 in phagocytes
1) Confidence 0.21 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2882833 Disease Relevance 0.48 Pain Relevance 0
IL-10 administration elevated CR3 expression in neutrophils and macrophages of infected mice, whereas infected and untreated mice displayed increased expression of Fc?
IL-10 Positive_regulation (elevated) of Gene_expression (expression) of CR3 in macrophages
2) Confidence 0.16 Published 2010 Journal The Journal of Experimental Medicine Section Abstract Doc Link PMC2882833 Disease Relevance 0.38 Pain Relevance 0
IL-10 administration elevated CR3 expression in neutrophils and macrophages of infected mice, whereas infected and untreated mice displayed increased expression of Fc?
IL-10 Positive_regulation (elevated) of in neutrophils Gene_expression (expression) of CR3 in macrophages
3) Confidence 0.05 Published 2010 Journal The Journal of Experimental Medicine Section Abstract Doc Link PMC2882833 Disease Relevance 0.38 Pain Relevance 0

General Comments

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