INT314538

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ptger2) extracellular space (Il10) extracellular region (Il10)
plasma membrane (Ptger2) intracellular (Il10) signal transducer activity (Ptger2)
Anatomy Link Frequency
monocytes 2
Il10 (Mus musculus)
Ptger2 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 14 74.40 Quite High
Inflammation 9 36.44 Quite Low
dexamethasone 2 28.32 Quite Low
Inflammatory response 9 14.08 Low Low
imagery 4 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 62 90.68 High High
Meningitis 37 84.88 Quite High
Apoptosis 19 79.48 Quite High
INFLAMMATION 21 75.76 Quite High
Adhesions 1 56.68 Quite High
Bacterial Meningitis 3 55.92 Quite High
Injury 5 51.20 Quite High
Hearing Impairment 2 25.20 Quite Low
Pneumococcal Meningitis 1 10.24 Low Low
Bacteremia 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been demonstrated that IL-10 inhibits the production of PGE-2 induced by LPS in monocytes (Niiro et al., 1994); however, PGE-2 generated during efferocytosis enhanced the production of IL-10 (Medeiros et al., 2009).
IL-10 Negative_regulation (inhibits) of Gene_expression (production) of PGE-2 in monocytes
1) Confidence 0.02 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2882833 Disease Relevance 0.65 Pain Relevance 0.04

General Comments

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