INT314619

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Context Info
Confidence 0.29
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.75
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ZGLP1)
Anatomy Link Frequency
plasma 2
intestine 1
ZGLP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 13 99.96 Very High Very High Very High
Central nervous system 1 42.72 Quite Low
Bile 2 33.00 Quite Low
Bioavailability 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Parenteral administration 4 5.00 Very Low Very Low Very Low
nud 4 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 217 96.28 Very High Very High Very High
Disease 25 94.64 High High
Amebiasis 1 94.28 High High
Overnutrition 26 93.76 High High
Obesity 32 88.00 High High
Infection 5 77.32 Quite High
Insulin Resistance 10 73.48 Quite High
Of Sheep Progressive Interstitial Pneumonia 3 73.00 Quite High
Visna 3 72.76 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 68.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GIP is secreted by K cells from the upper small intestine and GLP-1 is mainly produced in the enteroendocrine L cells located in the distal intestine.
Gene_expression (produced) of GLP-1 in intestine
1) Confidence 0.29 Published 2010 Journal Core Evidence Section Body Doc Link PMC2963920 Disease Relevance 0.64 Pain Relevance 0
Hence, attempts were made to find out GLP-1 like substances in other animal species and/or synthesize compounds with GLP-1 like (GLP-1 agonists) action having longer plasma half-life[1].
Gene_expression (synthesize) of GLP-1 in plasma associated with agonist
2) Confidence 0.22 Published 2010 Journal Indian Journal of Pharmaceutical Sciences Section Body Doc Link PMC2883206 Disease Relevance 1.05 Pain Relevance 0.05
Hence, attempts were made to find out GLP-1 like substances in other animal species and/or synthesize compounds with GLP-1 like (GLP-1 agonists) action having longer plasma half-life[1].
Gene_expression (synthesize) of GLP-1 in plasma associated with agonist
3) Confidence 0.15 Published 2010 Journal Indian Journal of Pharmaceutical Sciences Section Body Doc Link PMC2883206 Disease Relevance 1.05 Pain Relevance 0.05
This association was particularly interesting to author GKW as it suggests that this protozoan might be responsive to as-yet-uncharacterized GATA-like or Gal4-like transcription factors as a trigger for the expression of the multi-drug resistance trait.
Gene_expression (expression) of GATA-like
4) Confidence 0.04 Published 2010 Journal J Biomed Discov Collab Section Body Doc Link PMC2990276 Disease Relevance 1.01 Pain Relevance 0

General Comments

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