INT314709

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Context Info
Confidence 0.41
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.71
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Fbxo4)
Fbxo4 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 5 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 91 97.72 Very High Very High Very High
Breast Cancer 123 92.52 High High
Disease 16 19.92 Low Low
Polyploidy 1 17.48 Low Low
Aging 5 5.72 Low Low
Metastasis 10 5.00 Very Low Very Low Very Low
Recurrence 9 5.00 Very Low Very Low Very Low
Carcinoma 7 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 6 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, Barbash et al140 demonstrated that attenuation of cyclin D1 SCFFbx4 E3 ubiquitin ligase activity occurs frequently in human cancer and may represent a common mechanism of overexpression and deregulation of cyclin D1.
Negative_regulation (attenuation) of Fbx4 associated with cancer
1) Confidence 0.41 Published 2010 Journal Clinical Medicine Insights. Oncology Section Body Doc Link PMC2883240 Disease Relevance 0.71 Pain Relevance 0

General Comments

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