INT314766

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Context Info
Confidence 0.30
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.04
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Mafa) DNA binding (Mafa)
Anatomy Link Frequency
blood 1
Mafa (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosarcoma 2 100.00 Very High Very High Very High
Hyperglycemia 8 98.76 Very High Very High Very High
Diabetes Mellitus 64 95.64 Very High Very High Very High
Autoimmune Disease 2 55.44 Quite High
Severe Combined Immunodeficiency 2 45.80 Quite Low
Obesity 12 32.76 Quite Low
Hypoglycemia 6 5.00 Very Low Very Low Very Low
Graft Vs Host Disease 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Salivary Gland Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An exciting report demonstrated that expressing a specific combination of three transcription factors, Pdx-1, Ngn3, and musculoaponeurotic fibrosarcoma oncogene homolog A (MafA), resulted in amelioration of hyperglycemia.
Gene_expression (expressing) of MafA associated with hyperglycemia and fibrosarcoma
1) Confidence 0.30 Published 2010 Journal Korean Diabetes Journal Section Body Doc Link PMC2883354 Disease Relevance 0.50 Pain Relevance 0
Forced expression of Pdx-1 [38], MafA [39], or GLP-1 [40] in intestinal epithelia by adenovirus-mediated gene transfer induced the expression of insulin and lowered blood glucose levels in streptozotocin-induced diabetic animals.
Gene_expression (expression) of MafA in blood associated with diabetes mellitus
2) Confidence 0.30 Published 2010 Journal Korean Diabetes Journal Section Body Doc Link PMC2883354 Disease Relevance 0.54 Pain Relevance 0

General Comments

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