INT314856

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.34
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Cdc7, Cdkn2a) nucleus (Cdc7, Cdkn2a) cell cycle (Cdc7, Cdkn2a)
nucleoplasm (Cdkn2a) aging (Cdkn2a) DNA binding (Cdkn2a)
Anatomy Link Frequency
optic disc 3
Cdc7 (Mus musculus)
Cdkn2a (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 3 94.32 High High
Inflammation 3 93.04 High High
cytokine 3 86.60 High High
imagery 12 5.00 Very Low Very Low Very Low
Neuritis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 3 99.28 Very High Very High Very High
Myocardial Infarction 3 98.12 Very High Very High Very High
Cancer 15 96.80 Very High Very High Very High
Cataract 6 95.20 Very High Very High Very High
Fibrosis 3 94.32 High High
Autoimmune Disease 3 93.92 High High
INFLAMMATION 3 93.04 High High
Disease 18 92.12 High High
Melanoma 3 70.28 Quite High
Glioma 3 69.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although this region is associated with the optic disc area, the protein that CDC7 encodes for interacts with the CDKN2A protein associated with VCDR.
CDC7 Binding (interacts) of CDKN2A in optic disc
1) Confidence 0.28 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2883590 Disease Relevance 0.10 Pain Relevance 0
The CDKN2B/CDKN2A and CDC7/TGFBR3 loci influence the VCDR independently of optic disc area as these genes were not significantly associated with the optic disc area (p>0.05).
CDC7 Binding (loci) of CDKN2A in optic disc
2) Confidence 0.21 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2883590 Disease Relevance 1.15 Pain Relevance 0.14
Although this region is associated with the optic disc area, the protein that CDC7 encodes for interacts with the CDKN2A protein associated with VCDR.
CDC7 Binding (associated) of CDKN2A in optic disc
3) Confidence 0.21 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2883590 Disease Relevance 0.10 Pain Relevance 0

General Comments

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