INT314986

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ins1, CACNA1S) extracellular space (Ins1) extracellular region (Ins1)
plasma membrane (CACNA1S) carbohydrate metabolic process (Ins1) transmembrane transport (CACNA1S)
Anatomy Link Frequency
muscle fibers 1
Ins1 (Rattus norvegicus)
CACNA1S (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 6 25.52 Quite Low
sodium channel 25 5.00 Very Low Very Low Very Low
Action potential 14 5.00 Very Low Very Low Very Low
potassium channel 3 5.00 Very Low Very Low Very Low
Mexiletine 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
hyperexcitability 1 5.00 Very Low Very Low Very Low
repetitive firing 1 5.00 Very Low Very Low Very Low
local anesthetic 1 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypokalemic Periodic Paralysis 6 76.44 Quite High
Channelopathies 8 50.00 Quite Low
Paralysis 8 43.12 Quite Low
Hyperkalemia 8 38.84 Quite Low
Disease 10 36.64 Quite Low
Hypopituitarism 33 5.00 Very Low Very Low Very Low
Myotonic Disorders 13 5.00 Very Low Very Low Very Low
Congenital Myasthenic Syndromes 6 5.00 Very Low Very Low Very Low
Muscle Disease 6 5.00 Very Low Very Low Very Low
Hyperkalemic Periodic Paralysis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Control (red line), additional small (5 µS/cm2) depolarizing current and insulin-induced reduction of Kir conductance as in HypoPP (blue line), regions of instability (dashed line). b Fraction of rat diaphragm muscle fibers with normal membrane potentials after the reduction of [K+]o to different values, without (red) and with (blue) amphotericin B, a Na+ and K+ ionophore.
insulin Negative_regulation (reduction) of HypoPP in muscle fibers
1) Confidence 0.00 Published 2010 Journal Pflugers Arch Section Body Doc Link PMC2883924 Disease Relevance 0.08 Pain Relevance 0

General Comments

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