INT31505

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Context Info
Confidence 0.54
First Reported 1986
Last Reported 1986
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CRH) extracellular space (CRH) extracellular region (CRH)
nucleolus (FEM1B) nucleus (FEM1B) cytoplasm (FEM1B)
CRH (Homo sapiens)
FEM1B (Homo sapiens)
Pain Link Frequency Relevance Heat
Dynorphin 2 98.00 Very High Very High Very High
Opioid 2 84.96 Quite High
narcan 1 81.04 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Synthetic rat-human corticotropin releasing-factor (CRF), in doses between 10(-12) M and 10(-8) M, significantly stimulates the release of immunoreactive beta-endorphin and dynorphin-A from rat hypothalamic slices superfused in vitro.
CRF Positive_regulation (stimulates) of Gene_expression (Synthetic) of rat- associated with dynorphin
1) Confidence 0.54 Published 1986 Journal NIDA Res. Monogr. Section Abstract Doc Link 2893273 Disease Relevance 0 Pain Relevance 0.28

General Comments

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