INT315053

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.12
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (AKT1, RELA) nucleus (AKT1, RELA) cytoplasm (AKT1, RELA)
cytosol (AKT1, RELA) cell differentiation (AKT1) transport (AKT1)
AKT1 (Homo sapiens)
RELA (Homo sapiens)
Pain Link Frequency Relevance Heat
methotrexate 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 60 64.00 Quite High
Colon Cancer 43 50.00 Quite Low
Cancer 23 5.00 Very Low Very Low Very Low
Reprotox - General 1 10 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Repression 3 5.00 Very Low Very Low Very Low
Neuroblastoma 3 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, these results suggest that inhibition of AKT1 extensively augments Par-4/p65 interactions in cytosol and consequently blocks nuclear translocation of p65.


Negative_regulation (inhibition) of AKT1 Positive_regulation (augments) of p65 Binding (interactions) of
1) Confidence 0.10 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2883962 Disease Relevance 0.12 Pain Relevance 0

General Comments

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