INT315060

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Context Info
Confidence 0.53
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (BCL2) cell morphogenesis (BCL2) endoplasmic reticulum (BCL2)
intracellular (BCL2) cytoplasm (BCL2) cytosol (BCL2)
Anatomy Link Frequency
colon 1
PAR4 (Homo sapiens)
BCL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
methotrexate 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 1 10 99.64 Very High Very High Very High
Colon Cancer 43 98.88 Very High Very High Very High
Apoptosis 60 62.36 Quite High
Repression 3 50.40 Quite High
Cancer 23 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Neuroblastoma 3 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although levels of BCL2 mRNA (a pro-survival gene) were not significantly affected by Par-4 overexpression in HT29 colon cancer cells, we included BCL2 in immunoblotting assays since Par-4 has been shown to regulate BCL2 mRNA in prostate cancer cell lines [35].
Par-4 Regulation (regulate) of BCL2 in colon associated with colon cancer and reprotox - general 1
1) Confidence 0.53 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2883962 Disease Relevance 0.48 Pain Relevance 0

General Comments

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