INT315099

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Context Info
Confidence 0.55
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.36
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IGF1R) plasma membrane (IGF1R)
IGF1R (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 1 85.40 High High
Inflammation 29 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 25 97.24 Very High Very High Very High
Colon Cancer 44 76.12 Quite High
Apoptosis 62 69.92 Quite High
Cancer 103 54.00 Quite High
Liver Cancer 1 46.44 Quite Low
Reprotox - General 1 10 36.60 Quite Low
INFLAMMATION 30 5.00 Very Low Very Low Very Low
Death 8 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low
Metastasis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B p65 and p50 were significantly enriched at predicted binding elements on promoter regions of MAPK1, CDK5, SLC2A1, IGF1R, TUBB, BRAF, DROSHA, ITGB4, MT1X and MT1E, when compared with the no antibody ChIP-qPCR control and the nonspecific occupancy at ACTB (Figure 3B, C and 3D).
Localization (occupancy) of IGF1R
1) Confidence 0.55 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2883962 Disease Relevance 0.26 Pain Relevance 0
The optimal titer for each antibody (except for HercepTest and G11 directed against ERBB2 and IGF1R, Additionnal file 1-Table S2) was established based on negative and positive controls.
Localization (directed) of IGF1R
2) Confidence 0.38 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.10 Pain Relevance 0.04

General Comments

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