INT315268

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Gopc, Nfe2l2) cytoplasm (Gopc, Nfe2l2) transport (Gopc)
Golgi apparatus (Gopc) nucleus (Nfe2l2) DNA binding (Nfe2l2)
Gopc (Mus musculus)
Nfe2l2 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 4 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 17 91.20 High High
Stress 23 13.68 Low Low
Targeted Disruption 5 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NAPQI (Fig. 4A) and DNCB (Fig. 4B), which can covalently bind proteins and deplete GSH, increased Nrf2 activity and decreased NF-?
Fig Positive_regulation (increased) of Nrf2 Binding (activity) of
1) Confidence 0.10 Published 2010 Journal Biochemical Pharmacology Section Body Doc Link PMC2884179 Disease Relevance 0.09 Pain Relevance 0

General Comments

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